24 Negative And Positive Effects Of Aspirin On The Body

Aspirin is a common drug that is known for the ability to relieve pain then reduce the risks of other serious diseases like heart attacks and strokes. Aspirin can come in some forms including pills and tablets which are dissolved in powders, water, and oral gels. Some types of this drug can be bought from pharmacies but others are only suggested on prescription.

Aspirin has been widely used for various health conditions but the users should be always careful with the doses to avoid some side effects of aspirin. High doses of aspirin help relieve pain, reduce swelling, and reduce a high temperature along with a fever, so it is abused in a short term to relieve headaches, a cold and flu, toothache, general aches and pains, and period pains. Meanwhile, aspirin is used in a long term with low doses to stop the development of blood clots and make the blood less sticky for those with a heart attack, a stroke, peripheral arterial disease, and coronary artery bypass surgery.

Now, VKool.com would like to show you 24 negative and positive effects of aspirin on the body. This medicine, with a wide and popular use all over the world, should be known for all of its advantages and disadvantages in order to be properly taken. For those who don’t know what aspirin brings or causes to the health, just spend a few minutes reading our article to have more experience!

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24 Negative And Positive Effects Of Aspirin On The Body

Positive Effects Of Aspirin:

1. Relieve Headaches

Relieving headaches is known as the first one of the positive effects of aspirin for the health. If you are looking for a magical drug that removes headaches instantly, aspirin may be the best choice because there is no quicker and better drug to cure headaches than this medicine.

2. Cure Fever

Aspirin is also used to cure a fever. When you feel the symptoms ofa fever and your body is becoming an ache, a single aspirin tablet is needed to make you feel better. In fact, this medicine can solve minor fever or soreness caused by a cold.

3. Prevent Heart Attacks

Preventing the risk of heart attacks is one of the important positive effects of aspirin. The patients with this disease may know that putting an aspirin under their tongue is the best first aid for them because this medicine can dilute the blood and destroy clots effectively.

4. Protect Against Liver Damage

According to the studies conducted on rats before, aspirin, when taken with regular but low doses, can prevent the liver from damages. Therefore, it is particularly used to alcoholics.

5. Prevent Cancer

effects of aspirin - prevent cancer

Some research supposes that low doses of aspirin are really preventive medications against cancer because it can stall the growth and spread of cancer cells in the body.

6. Treat Bug Bites

Due to the anti-inflammatory properties, aspirin can be used to soothe the bug bites and insect bites that are also common and troublesome in an easy way.

7. Get Rid Of Acne

It may sound weird but aspirin is also helpful for the acne removal. It is due to the salicylic acid found in this medicine that can treat acnes effectively indeed. More clearly, powdered aspirin is suggested to apply onto nasty pimples for the purpose of getting rid of pimples and acnes quickly.

8. Cure Dandruff

Not only dose aspirin be used for internal health and skin problem but it is also used for the hair. In fact, dandruff is always a concern that can appear anytime though you wash your hair so often. As a recommendation, you can mix your shampoo with some powdered aspirin to keep dandruff at bay for a longer term.

Negative Effects Of Aspirin

9. Minor Side Effects

There are some minor side effects of aspirin that occur quite often and do not need medical attention. They are considered to be dizziness and vertigo, anxiety, belching, acid or sour stomach, discomforted, upset, and painful stomach, dry mouth, irritability, shaking, hyperventilation, trouble sleeping, and unusual tiredness and weakness. However, when the body adjusts during the treatment to the medicine, these side effects will go away. In addition, the healthcare professional may give you essential ways to prevent or reduce these side effects. In case these side effects continue, you should consult and check a health care professional to prevent them as soon as possible.

10. Gastrointestinal Problems

Causing some problems related to gastrointestinal system is one of the negative side effects of aspirin. In fact, Endoscopically identifiable gastric mucosal injuries appear in most of that receive are given doses of aspirin. For example, clinical evidence has shown that 3% of elderly patients using aspirin suffered from gastrointestinal bleeding while others with aspirin-containing rectal suppositories suffered from rectal stenosis and Anorectal ulceration as well. In addition, it has been indicated that there is an association between the use of aspirin and appendicitis [1].

The risks of developing digestive events like heartburn, ulcers, epigastric pain, and nausea may be lower in the patients with rheumatism who have not had gastrointestinal symptoms before and received low doses of aspirin, less than 650 mg per day.

The side effects of aspirin on the gastrointestinal system also include epigastric distress which occurs in about 83% of patients with the regular treatment of aspirin, abdominal pain or discomfort, nausea, vomiting, and endoscopically identifiable gastric mucosal injuries. Some more dangerous gastrointestinal effects are known as hemorrhage, peptic ulcers, esophageal ulcerations, perforation, and small bowel enteropathy.

11. Renal Problems

Renal problems are other side effects of aspirin for the health. In fact, the mechanism of the decrease in renal function caused by the aspirin consumption is associated with the hindrance of renal prostaglandin synthesis and regular reduction in the renal blood flow. In fact, vasodilating renal prostaglandins are significantly important in patients with an exhibition of arterial under fillings such as heart failure and cirrhosis. Therefore, the administration for those with high doses of aspirin has brought acute renal failure in some certain instances.

In addition, the renal side effects of aspirin include the decrease in glomerular filtration rate, especially in those with sodium restriction or reduction in effective arterial blood volume like the patients with advanced cirrhosis or heart failure or cirrhosis, papillary necrosis, interstitial nephritis, elevations in blood urea nitrogen, elevations in serum creatinine, hematuria, proteinuria, and renal failure.

12. Metabolic Problems

effects of aspirin - metabolic problems

Metabolic problems are also the side effects of aspirin, which includes dehydration and hyperkalemia. It has been reported in metabolic acidosis and respiratory alkalosis, particularly during salicylate toxicity. In addition, a case of hypoglycemia was also reported in a patient with hemodialysis while salicylates were reported to displace thyroxine (T4) and triiodothyronine (T3) from protein binding sites. And the initial effect is the increase in the free concentration of serum T4.

13. Hematologic Side Effects

The side effects of aspirin also include hematologic one that contains the increased blood fibrinolytic activity. Additionally, hypoprothrombinemia, thrombocyturia, thrombocytopenia, pancytopenia, and megaloblastic anemia have been rarely reported. Eosinophilia and aplastic anemia have been reported as well.

14. Cardiovascular Side Effects

According to the studies before, a 29-year-old female who followed the consumption of aspirin at the doses 1500 mg a day through several days suffered froma migraine developed chest pain, orthopnea, and tachycardia. However, after discontinuation of using aspirin, these symptoms of the patient are promptly resolved, which means there might be some association between aspirin consumption and cardiovascular system.

The cardiovascular side effects include salicylate-induced variant angina, conduction abnormalities, ventricular ectopy, and hypotension, especially during salicylate toxicity. Additionally, at least a situation of fluid retention has been reported to simulate acute congestive heart failure during aspirin therapy. And antiplatelet therapy has been related to deterioration of intracerebral hemorrhage as well.

15. Nervous System Side Effects

The side effects of aspirin also include ones for the nervous system. These side effects include headaches, dizziness, confusion, agitation, coma, cerebral edema, cranial hemorrhage, seizures, and lethargy. In addition, subjective hearing loss and tinnitus can also occur. According to some investigators, the modest doses of aspirin can cause decreased frequency selectivity and then probably impair a hearing performance, especially in the formation of background noise.

However, other investigators have supposed that tinnitus is not really a believable indicator of salicylate toxicity as some before. It is because the patients with high frequency of hearing loss can suffer from difficulty perceiving tinnitus. Additionally, a study conducted on the patients with rheumatoid arthritis and tinnitus has shown that no there have no greater salicylate levels than patients without tinnitus. And younger patients may be more likely perceive tinnitus than elderly patients as well.

16. Respiratory Problems

The side effects of aspirin also include some respiratory problems that have been known as hyperpnea, tachypnea, and pulmonary edema.

In addition, aspirin desensitization has been also abused to reduce disease activity and the requirement of systemic corticosteroids in those who suffer froman aspirin-exacerbated respiratory disease.

17. Hypersensitivity

The reason aspirin inducing hypersensitivity may be the regulation of the 5-lipoxygenase pathway of the arachidonic acid metabolism, which results in an increase in creating the products of 5-lipoxygenase like leukotrienes).

In fact, Hypersensitivity side effects of aspirin include conjunctivitis, rhinitis, bronchospasm, anaphylaxis, urticaria, and angioedema. According to the clinical trial on the aspirin sensitivity [2], nasal polyps, and bronchial asthma, approximately 30% of asthmatics are sensitive to aspirin indeed.

18. Dermatologic Problems

effects of aspirin - dermatologic problems

There are some sermatolgic problems associated with the side effects of aspirin known as a lichenoid eruption and Stevens-Johnson syndrome. Moreover, the aspirin therapy has been indicated to be associated with some cases of unilateral aquagenic wrinkles in the papuloery throderma and palms.

19. Oncologic Side Effects

Oncologic side effects are also the results of aspirin consumption, which includes some reports of pancreatic cancer. However, there have been several epidemiologic studies supposing that the chronic aspirin use could prevent the risks of large bowel neoplasms. Up to now, there need more studies to make this point clearer as well.

20. Bleeding

Bleeding is considered as one of the sides effects of aspirin consumption. While vomiting, stomach upset, indigestion, heartburn, and dizziness are common side effects of aspirin, bleeding is the most dangerous side effect of this medicine. The risks of bleeding will be more increased when the patients take aspirin along with other anti-clotting medicines like warfarin.

There are some signs and symptoms of bleeding that you should be aware of including nosebleeds that frequently occurs and take longer time to stop; bleeding from wounds, cuts, and scrapes that need more time to stop; bruising that easily occurs and difficult to heal, coughing up blood; dark or bloody vomit; unusual pains, swelling, and discomfort; severe headaches and dizziness; trouble swallowing and breathing; red or black bowel motions, red or dark brown urine, and heavier menstrual periods.

Just a fall or injury can cause internal bleeding that is, of course, not obvious, so you should report any injuries such as cuts, falls, scratches, bruising, and accidents to your doctor to check out if there is any bleeding inside.

21. Allergic Side Effects

Other side effects of aspirin are known as allergic reactions. A patient with aspirin allergy may experience some of the symptoms such as swelling of the tongue, lips, and face which makes swallowing more difficult; sudden and severe itching and skin rash, wheezing, asthma, and shortness of breath.

Because an allergic reaction is serious, if you think you are suffering from an allergic reaction to aspirin, you should go to the nearest hospital as soon as possible.

22. Other Side Effects

There are some other side effects of aspirin as listed later. The first one is Reye's syndrome that scientifically involves in vomiting, dysfunction, and neurologic dysfunction during or a bit later an acute viral infection. In addition, the side effects of aspirin on Reye's syndrome occur in children who have had an acute viral illness but reported to be quite rare in adults.

The second are hepatic side effects that contain hepatotoxicity and cholestatic hepatitis. And the final ones are musculoskeletal side effects that include rhabdomyolysis.

23. Health Conditions And The Use Of Aspirin

Before you begin using aspirin or any types of medication, you should inform your doctor of your probable allergies or medical conditions you may have or if you are a pregnant or breastfeeding woman, and other significant information about your health so that she/he can give you the suitable medicine and doses. The use of aspirin should be careful in the following cases:

Alcohol: Alcohol can increase the risks of developing stomach bleeds in people taking aspirin, so anyone who uses aspirin on a regular basis should avoid or limit the intake of alcohol.

Liver function: Because aspirin can give certain effects to the function of the liver, people with liver diseases or decreased liver function should discuss with your doctor to get necessary instructions.

Diabetes: High doses of aspirin can result in the reduction of blood glucose levels, which then changes the insulin needs in those with diabetes. Therefore, anyone who has diabetes or is at the risk of developing diabetes should consult a professional how aspirin can affect his/her medical condition, as well as which doses are effective, and if she/he needs any special monitoring.

Gout: Acetylsalicylic acid or aspirin can boost the uric acid level in the body, which may cause gout to flare up. In addition, aspirin can reduce the effectiveness of medications in the treatment of gout. It is the reason why anyone with a medical history of kidney stones or gout should discuss with a professional before using aspirin for their certain purposes. And if you have painful and swollen joints or difficult urination, go to the hospital as soon as possible.

Kidney function: As aspirin can bring some certain effects to the kidney function, people with kidney diseases or reduced kidney function should consult your doctor to have the best instructions.

Bleeding: As mentioned above, bleeding is one of the side effects of aspirin, which is due to its antiplatelet properties possible to prevent blood from clotting. Therefore, the patients with an aspirin therapy should be monitored, particularly when you are also using anticoagulant medications like warfarin.

Surgery: To avoid unwanted effects of aspirin, this medicine should be stopped to use at least a week before an elective surgery in case of bleeding. So, if you have been planned for surgery despite a minor surgery like dental extractions, you should talk to your pharmacist or doctor to know when you need to stop taking aspirin.

Breathing problems: Breathing problems are side effects of aspirin also the factor making the patients easier to experience an allergic reaction to this medicine. People with a medical history of long-term breathing problems, asthma, or allergic conditions like nasal polyps or hay fever are possible to suffer from difficult breathing and allergic reactions that are known as the side effects of aspirin. Hence, they should discuss with their doctor to know how to use aspirin most effectively.

Pregnancy: Daily doses of aspirin at the amounts of more than 300 mg may cause a longer pregnancy. If the pregnant women take aspirin in the third trimester, it may develop the risks of bleeding in both the mother and baby. In addition, it can also result in premature arterial duct closure of the fetus that is known as a passageway in the heart. In brief, aspirin should be avoided during pregnancy otherwise the pregnant women have to contact their doctor as soon as possible if they continue to use this medicine.

Breastfeeding: Because acetylsalicylic acid or aspirin can pass into breast milk of breastfeeding women, they should avoid using aspirin during this period to prevent the risks this medicine affects their babies. Additionally, they should talk to a doctor to get more necessary information.

Other conditions: People with a medical history of stomach ulcers, anemia or low blood iron levels, a tendency to bleed, and blood clotting disorders should discuss their doctors to know if aspirin can affect their conditions as well as how to use it in certain cases.

24. Children And Adults With Aspirin Intake

Because of many side effects of aspirin for the health, this medicine should be decreasingly used for adults and avoided by children. In fact, children, teenagers, and the young are advised to not take aspirin though they are suffering from flu-like illnesses, chickenpox, or influenza as it can increase their risks of Reye's syndrome that is known as a possible threatening condition to the health causing liver or brain damage.

For adults who often take aspirin for the purpose of preventing heart attack or stroke, they are given a low dose of aspirin that is small but also impossible to infants. A standard low dose of aspirin should be 81 mg or probably 75 mg while regularly strong aspirin dose is 325 mg. Particularly, the patients over 65 years old often experience a stronger reaction to the effects of aspirin, so they need smaller doses. In the most careful cases, the patients should consult their doctors to get the correct dosage.

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After reading the article on 24 negative and positive effects of aspirin on the body in our main Health page, hope that you can get more information about this medicine including its benefits and other side effects so that find out suitable doses and treatment as soon as possible. Please let us know if you have any question by leaving them below and share with us other effects of aspirin if you really get.

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