Contrave Review (UPDATED 2024) — Is It Safe?

502 Review(s)
AVG Rating: 3.8/10

This is one product that you can’t afford to consider without knowing the risks. That’s why we’ve decided to do some research into this weight loss pill and see if it measures up to the hype it’s caused. Remember: don’t believe everything you’re advertised.
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Check out our review below and decided for yourself whether this product is worth considering, and make sure you do your own research on your own. Your health depends on it.

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Contrave Overview

Contrave is a pill intended to help people who are trying to lose weight. It’s a prescription drug, meaning that it’s been approved by the FDA (unlike nutritional supplements, which generally aren’t). You require a prescription in order to purchase Contrave, as it cannot be sold over-the-counter legally.
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Each dose comes with 8mg of naltrexone and 90mg of bupropion, and users are required to take the pill in creasing amounts – starting off with just one pill in the morning daily, followed by two (one in the morning, one in the evening) the next week, and increasing until they are taking two pills in the morning and two in the evening. Some patient dosing may differ.

Contrave is made by Orexigen, a pharmaceutical company based in California. This company is currently the main supplier of Contrave’s unique blend of ingredients. They were served with a warning from the FDA only last year for running a misleading television advertisement that, according to the FDA, didn’t adequately detail the possible dangers and side effects from using Contrave. It’s not a great sign when a company deliberately tries to hide the potentially harmful side of their product for personal gain.

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Contrave Claims

This pill is supposed to be able to help users lose weight by reducing their desire to eat. With long-term use, therefore, people using the pills are supposed to see their eating habits become healthier, their appetite and desire for food lower, with the overall result of taking in fewer calories and thus lose weight. They claim that people taking the product can keep weight off as well, keeping the gains they’ve made.

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Contrave Ingredients

Contrave contains only two active ingredients:

  • Naltrexone
  • Bupropion

Naltrexone is a medication that’s usually prescribed for people who have a dependence on drugs or alcohol. It’s used in other medications as well as Contrave. It comes with potential side effects, like sleeplessness, nausea, and headaches, and it could take weeks to really work.

Bupropion is an antidepressant that’s also been used to help people quit smoking. On its own, it has not been approved by the FDA for weight loss – only in combination with naltrexone was it approved. It also comes with potential side effects like sexual dysfunction, weight gain, and sleeplessness.

According to the FDA, Contrave must be advertised with warnings that it can cause suicidal thoughts.

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The Science Behind Contrave

The naltrexone in this product is supposed to work by preventing activation of the “reward” center in the brain while eating, leading to people getting less chemical “pleasure” from eating, thus (hopefully) lowering the desire to eat. Bupropion also affects the brain’s chemistry, specifically serotonin. Together, these two medications are supposed to help curb the “cravings” that overweight people have for food, and making it easier to change eating habits.

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Word on the Street About Contrave

Contrave seems to have its fans, but not all of the reviews we’ve seen are positive. Some customers related that “I didn’t feel many side effects” and “it helped me with my cravings.” Others said “my appetite decreased” and “I’ve been eating less since taking Contrave.

Others had big problems with this stuff. “I’ve been vomiting” one user warned, with others chiming in with their own side effect problems – “I’ve been having headaches,” “dry mouth,” and more. Another said they felt “terrible tightness in their chest” and “it makes me nauseous, even after I stopped taking it.

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Is Contrave Worth Trying?

To us, his product’s benefits don’t outweigh its negatives. Basically what you have here is an anti-addiction pill that’s focused at people who overeat. While food can be an addiction, Contrave doesn’t really seem like the best option. For one, it comes with lots of side effects (including suicidal thoughts!), but that’s not all: the company admits on their website that everyone will have different experiences, and that it may not work for everyone.

It’s also expensive: as much as $165 (or more) per prescription.

If you have an addiction to food, your doctor may suggest Contrave. For most people, however, this product just isn’t a great choice.

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Contrave vs Wellbutrin

These are slightly different products, but they have some things in common. Contrave is a behavioral medication that changes the brain’s chemistry, preventing people from feeling the “reward” function of eating (in an attempt to wean them off of food cravings), while Wellbutrin is an antidepressant that can also be used to treat smoking addiction. Both contain bupropion, and so that part of their function is similar. Wellbutrin can cost around $87 depending on the pharmacy you go to, while Contrave can cost upwards of $150-$160.

Contrave vs Phentermine

These products are both prescription medications, but they don’t work in the same way. While Contrave focuses on helping change the brain’s “reward” system and helping people avoid food cravings, phentermine is a stimulant that’s used as an appetite suppressant. So while both are intended to help people eat less, they do so by different methods. Phentermine is much cheaper than Contrave, costing between $9 and $35, while Contrave can cost almost $200.

Contrave vs Saxenda

Both of these products are focused on helping people change their eating habits so that they can lose weight. Contrave affects the “reward” center in the brain to control cravings, while Saxenda makes your brain think it’s less hungry.
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Thus both are supposed to lead to people wanting to eat less. Both are supposed to be used alongside a healthy diet and exercise, not used alone. Another big difference between them is that Contrave is a pill, while Saxenda comes in an injectable shot. Saxenda is also much more expensive than Contrave.

Frequently Asked Questions

  1. Where can I read Contrave reviews?
    You can read them at, where we often find reviews for prescription medicine.
  2. Where can I get a coupon for Contrave?
    Contrave offers one that you can sign up for on their website.
  3. What’s the dosage for Contrave?
    8mg of naltrexone, and 90mg of bupropion per dose.
  4. Can I buy Contrave online?
    The Contrave website offers a way to “talk to a doctor online” so that you can get a quick prescription written out for you, after which they can ship it to you.
  5. What are the side effects from using Contrave?
    Seizures, blood pressure spikes, hypoglycemia, liver damage, hepatitis, and manic episodes.
  6. How does Contrave dosing work?
    Your doctor will have more information about that, as it can vary from person to person.
  7. Does Contrave work?
    According to the FDA, it works well enough for them to give it their stamp of approval, for what that’s worth.
  8. Do I need a login to buy Contrave?
    On their main website yes, it looks like you do.

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So What Really Works?

If you want a pill that can help you lose weight without worrying about changing your brain chemistry or giving you horrible side effects, we recommend people try Sletrokor. Instead of a medicine, it’s a natural dietary supplement that contains ingredients found in nature that can help the body drop extra pounds faster by supporting a higher metabolism, among other benefits. It contains no artificial ingredients or additives, and is made in the USA in an FDA-registered facility. This is the pill we recommend to anyone looking for a safe, healthy way of reducing their weight.

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